Outcomes | Sub-Group Comparison of Meta-Analysis | # of Individual Studies Included in Meta-Analysis | Number of Participants Included in Meta-Analysis | Domain | Weighted Mean Difference (WMD) | 95Â % Confidence Interval | P value of overall effect | I2 statistic (p value for heterogeneity) | Interpretation |
---|---|---|---|---|---|---|---|---|---|
Health-Related Quality of Life (SF36 Questionnaire) | Aerobic (constant or interval) exercise or combined aerobic and PRE compared with no exercise | 2 studies (Maharaj 2011 [29]) | 59 | General Health | 4.73 | 1.72, 7.74 | 0.002a | 0 % (p = 0.78) | Significant improvement in change in General Health subscale score favouring exercisers compared with non-exercisers. |
59 | Mental Health | 11.58b | 1.35, 21.81 | 0.03a | 87 % (p = 0.006) | Significant (and potential clinically important) improvement in change in Mental Health subscale score favouring exercisers compared with non-exercisers. | |||
59 | Role Physical | 6.56 | 3.17, 9.96 | 0.0002a | 0 % (p = 0.53) | Significant improvement in change in Role Physical subscale score favouring exercisers compared with non-exercisers. | |||
59 | Role Emotional | 10.95b | 8.19, 13.71 | <0.0001a | 0 % (p = 0.40) | Significant (and potential clinically important) improvement in change in Role Emotional subscale score favouring exercisers compared with non-exercisers. | |||
59 | Pain | −6.59 | −9.83, −3.36 | <0.0001a | 0 % (p = 0.40) | Significant reduction in change in Pain subscale score favouring non-exercisers compared with exercisers. | |||
59 | Physical Functioning | 16.30b | 6.89, 25.72 | 0.0007a | 67 % (p = 0.08) | Significant (and potential clinically important) improvement in change in physical function subscale score favouring exercisers compared with non-exercisers. | |||
59 | Social Functioning | 2.73 | −4.84, 10.30 | 0.48 | 57 % (p = 0.13) | No difference in change in Social Functioning subscale score among exercisers compared with non-exercisers. | |||
59 | Energy/Vitality | 5.03 | 1.33, 8.72 | 0.008a | 0 % (p = 71) | Significant improvement in change in Energy/Vitality subscale score favouring exercisers compared with non-exercisers. | |||
472 | Overall Pooled Effect SF36 Subscale Scores | 6.47 | 3.18, 9.75 | <0.00001a | 87 % (p < 0.00001) | Significant improvement in SF36 subscale scores favouring exercisers compared with non-exercisers. | |||
Profile of Mood States (POMS) Scale | Aerobic (constant or interval) exercise compared with no exercise | 65 | POMS Scale | −7.68b | −13.47, −1.90 | 0.009a | 94 % (p < 0.0001) | Significant (and potential clinically important) improvement in depression-dejection scores favouring exercisers compared with non-exercisers. |